Indications
- Adults with moderate to severe rheumatoid arthritis (joint pain, swelling, stiffness)
- People whose symptoms did not improve with methotrexate
- People who cannot take methotrexate due to side effects.
Safety info from PI for patient use
Get Immediate Care
Contact your doctor right away if you notice signs of infection, chest pain, or trouble breathing. Don't wait for symptoms to worsen before seeking help.
How to Handle Blood Clots
This medicine may raise the risk of serious blood clots. Watch for swelling, warmth, or pain in your legs, and get medical help immediately if they appear.
Chances of Risk
Some patients may experience side effects. Talk to your healthcare provider about possible risks and any allergic reactions before starting treatment.
Safety Information
- Serious Warnings: JAKURA may cause serious, potentially fatal infections and major adverse cardiovascular events (MACE).
- TB Testing: You should be tested for latent tuberculosis before starting treatment.
Warnings & Precautions
- Gastrointestinal Risk: Use with caution if you have a history of stomach or intestinal problems (like diverticulitis).
- Lab Work: Routine blood tests are required to monitor your liver, kidneys, and blood cell counts.
Contraindications (When to avoid the drug)
Allergies
If you are allergic to tofacitinib or any of its ingredients.
Active tuberculosis
If you have active tuberculosis or a serious infection like sepsis.
Liver problems
If you have severe liver problems.
Pregnancy
If you are pregnant or breastfeeding.
Side Effects
|Common
Upper respiratory tract infections.
Headache.
Diarrhea.
Nasopharyngitis (common cold).
|Other
Increased cholesterol levels.
Skin rash.